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Is Polyoxyl 35 Castor Oil halal?

Polyoxyl 35 Castor Oil is classified halal for halal use with High confidence. A non-ionic surfactant produced by reacting castor oil (from the castor bean) with ethylene oxide; used to solubilise lipophilic drugs in IV and oral preparations. Plant-derived; halal. Note: it has a reputation for triggering hypersensitivity reactions in some patients (a clinical not a fiqh issue).

Solubiliser / surfactant · Confidence: High

Also known as: Cremophor EL, Kolliphor EL, PEG-35 castor oil

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What it is

A non-ionic surfactant produced by reacting castor oil (from the castor bean) with ethylene oxide; used to solubilise lipophilic drugs in IV and oral preparations.

Source:FDA IIG — Polyoxyl 35 castor oil

Why it's here

Allows poorly water-soluble actives such as paclitaxel, ciclosporin, and some IV anaesthetics to be dosed in aqueous vehicles.

See:FDA IIG — Polyoxyl 35 castor oil

Why it may matter

Plant-derived; halal. Note: it has a reputation for triggering hypersensitivity reactions in some patients (a clinical not a fiqh issue).

Source:FDA IIG — Polyoxyl 35 castor oil

Common sources
  • Plant (castor bean)

Reason codes

plantDerived

Evidence & citations1

Audit

Common questions

Is Polyoxyl 35 Castor Oil halal?
RxHalal currently classifies Polyoxyl 35 Castor Oil as HALAL (High confidence). Plant-derived; halal. Note: it has a reputation for triggering hypersensitivity reactions in some patients (a clinical not a fiqh issue). This is information only — not a fatwa or medical advice.
What is Polyoxyl 35 Castor Oil used for in medicines?
A non-ionic surfactant produced by reacting castor oil (from the castor bean) with ethylene oxide; used to solubilise lipophilic drugs in IV and oral preparations. Allows poorly water-soluble actives such as paclitaxel, ciclosporin, and some IV anaesthetics to be dosed in aqueous vehicles.
What are common sources of Polyoxyl 35 Castor Oil?
Common sources include: Plant (castor bean). Manufacturers often do not disclose which source is used.