Is Mannitol halal?
Mannitol is classified halal for halal use with High confidence. A sugar alcohol used as a non-cariogenic sweetener and tablet diluent. Not ethanol. Sugar alcohol — not beverage alcohol — halal.
Excipient (sweetener / diluent) · Confidence: High
Also known as: E421, D-mannitol
Looks Halal Ask pharmacist
What it is
A sugar alcohol used as a non-cariogenic sweetener and tablet diluent. Not ethanol.
Source:FDA IIG
Why it's here
Bulks chewables and IV osmotic diuretic.
See:FDA IIG
Why it may matter
Sugar alcohol — not beverage alcohol — halal.
Source:FDA IIG
Common sources
- Plant fermentation of fructose / sucrose
Reason codes
plantDerived
Evidence & citations1
AuditCommon questions
- Is Mannitol halal?
- RxHalal currently classifies Mannitol as HALAL (High confidence). Sugar alcohol — not beverage alcohol — halal. This is information only — not a fatwa or medical advice.
- What is Mannitol used for in medicines?
- A sugar alcohol used as a non-cariogenic sweetener and tablet diluent. Not ethanol. Bulks chewables and IV osmotic diuretic.
- What are common sources of Mannitol?
- Common sources include: Plant fermentation of fructose / sucrose. Manufacturers often do not disclose which source is used.
Medicines using this excipient
8 total2 halal6 uncertain0 concern
- Humira 40 mg Pen (adalimumab)· AbbVieLooks Halal
- Trulicity 0.75 mg Pen (dulaglutide)· Eli LillyLooks Halal
- Vitamin B12 1000 mcg Sublingual Tablet (cyanocobalamin)· Nature MadeUncertain
- Ondansetron 4 mg Orally Disintegrating Tablet (generic Zofran ODT)· Glenmark PharmaceuticalsUncertain
- Tradjenta 5 mg Tablet (linagliptin)· Boehringer IngelheimUncertain
- Aciphex 20 mg Tablet (rabeprazole)· Eisai Inc.Uncertain
Seen most often in these conditions
Where this excipient turns up across RxHalal's tracked treatment categories.